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CATH Superfamily 1.10.20.10

Histone, subunit A

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Histone, subunit A
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
Histone H3
3000 - - 95.5
2
Histone H4
1458
3D
 5ja4B00 - 94.1
3
Histone H2B
1405
3D
 3w97H00 - 96.5
4
Histone H2A
1328
3D
 5z23C00 - 80.4
5
Histone H2A
1028
3D
 5z30G00 - 92.0
6
Nuclear transcription factor Y subunit gamma
891
3D
 4csrB00 - 95.1
7
Histone H4
875
3D
 4kudF00 - 83.2
8
Histone H2A
675
3D
 6genF00 - 83.7
9
Histone H2A
551 - - 73.3
10
Histone H3
541 - - 85.2
11
Transcription initiation factor TFIID subunit 12
535
3D
 1h3oD00 - 97.1
12
Histone H4
530
3D
 6genD00 - 97.0
16
Histone H2B
499
3D
 4khaA03 - 92.2
13
Core histone macro-H2A
495
3D
 2f8nG00 - 88.2
14
Histone H2B
485
3D
 4wnnH00 - 78.7
15
Transcription initiation factor TFIID subunit 4B
447
3D
 1h3oC00 - 100.0
17
Ccaat-binding factor complex subunit
431
3D
 4g92C00 - 75.0
18
Transcription initiation factor TFIID subunit 9
407
3D
 1tafA00 - 98.5
19
Negative cofactor 2 beta
386
3D
 1jfiB00 - 98.0
85
Histone H3.2
383
3D
 6ir9e00 - 75.2
20
Histone H2A
373 - - 70.9
21
Histone H2A
333 - - 71.0
22
Histone H2A
298 - - 86.7
23
transcription initiation protein SPT3 homolog
288 - - 99.2
24
Histone H3
279 - - 88.3
25
Transcription initiation factor TFIID subunit 11
256
3D
 1bh9B00 - 92.1
103
Histone H2A type 1
251
3D
 6o1dG00 - 65.1
26
Histone H2A
244 - - 80.0
27
Nuclear transcription factor Y subunit beta
240
3D
 4csrA00 - 68.2
28
Transcription initiation factor TFIID subunit 13
235
3D
 1bh9A00 - 95.3
29
son of sevenless homolog 1 isoform X1
227
3D
 3ksyA01 - 73.1
30
Transcription initiation factor TFIID subunit 6
189
3D
 1tafB00 - 93.1
31
transcription initiation factor TFIID subunit 8 isoform X2
188
3D
 4wv4B00 - 35.4
32
dr1-associated corepressor isoform X1
177
3D
 1jfiA00 - 74.4
33
Transcription initiation factor TFIID complex subunit
175 - - 95.9
34
STAGA complex 65 subunit gamma
160 - - 96.5
35
Nuclear transcription factor Y subunit B-3
157 - - 77.9
36
CBF/NF-Y family transcription factor
146 - - 80.2
37
Transcription initiation factor TFIID subunit 12
138 - - 78.4
38
dr1-associated corepressor homolog
122 - - 62.0
44
Histone H3.3
112
3D
 5ja4A00 - 58.6
39
Nuclear transcription Y subunit beta
110 - - 46.0
40
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L
109 - - 89.9
76
Histone H4
104
3D
 6ir9f00 - 53.1
41
DNA polymerase epsilon subunit 3
104 - - 88.1
42
Transcription initiation factor TFIID subunit 13
101 - - 61.9
43
Histone H2B
99 - - 92.4
45
Histone H2B
88 - - 67.7
46
transcription initiation factor TFIID subunit 6
82 - - 68.1
47
Histone H3
77
3D
 1kx5E00 - 45.1
48
Chromatin accessibility complex subunit 1
73 - - 93.9
49
Nuclear transcription factor Y subunit B-6
73
3D
 5g49A00 - 84.4
53
Centromere protein W
72
3D
 3vh6W00 - 75.3
63
Centromere protein S
72
3D
 4ne6C00 - 79.6
51
DNA polymerase epsilon 4, accessory subunit
70 - - 75.0
50
centromere protein T isoform X2
70 - - 52.1
52
Histone H2A
69 - - 25.8
54
Putative histone H1.5-like
66 - - 85.2
55
Transcription initiation factor TFIID subunit 11
62 - - 77.7
56
Transcription initiation factor TFIID subunit 3
62 - - 40.0
57
ankyrin repeat and BTB/POZ domain-containing protein 2
59 - - 73.0
58
Histone H4
58 - - 53.5
59
Transcription initiation factor TFIID subunit beta
57 - - 76.2
65
Histone H3-like centromeric protein A
53
3D
 6o1dE00 - 71.8
60
BTB domain containing 11
50 - - 49.1
61
TFIID subunit
45 - - 93.5
62
Nuclear transcription factor Y subunit C
45 - - 98.5
64
Transcription initiation factor TFIID subunit 9
41 - - 77.5
66
H2B histone family member W testis-specific
40 - - 89.1
67
Transcription initiation factor TFIID subunit 13
37 - - 72.9
68
Nuclear factor Y transcription factor
36 - - 73.7
71
Transcription factor TFIID complex subunit
33 - - 90.3
69
Transcription initiation factor TFIID subunit
33 - - 82.8
70
Nuclear transcription factor Y subunit C-3
33 - - 59.8
72
Transcriptional activator spt7
32 - - 88.3
73
Histone H4
31 - - 45.5
74
dr1-associated corepressor
29 - - 46.0
78
Histone H3
28 - - 44.5
77
Histone H3 variant
28 - - 85.6
75
WGS project CABT00000000 data, contig 2.56
28 - - 95.4
79
Transcription initiation factor TFIID subunit 6, putative
27 - - 22.1
80
transcription initiation factor TFIID subunit 11 isoform X2
26 - - 26.9
82
Transcriptional activator, variant
25 - - 54.6
83
nuclear transcription factor Y subunit gamma isoform X4
25 - - 46.0
81
Histone H3, putative
25 - - 45.3
87
Probable histone 3
23 - - 78.5
84
Histone H2B
23 - - 33.8
86
Histone H2A
23 - - 93.1
89
Histone H2A
22 - - 66.9
88
Histone H3-like centromeric protein CSE4
22 - - 91.8
91
Histone H2A
21 - - 31.2
90
DNA polymerase epsilon subunit 3
21 - - 79.4
92
Protein MHF1-like isoform A
20 - - 74.2
93
Histone H2A
20 - - 92.1
94
CCAAT-binding transcription factor, putative
19 - - 5.8
96
Histone H3
18 - - 91.2
97
Histone H2A
18
3D
 6a7uA00 - 56.9
95
Histone H2A
18 - - 92.2
115
Histone H4
17
3D
 1p3oB00 - 42.7
101
Transcriptional activator SPT7
16 - - 64.4
98
Apoptosis-inducing TAF9-like domain 1 family protein, putative
16 - - 56.9
102
Histone H3-like centromeric protein CSE4
16 - - 86.9
100
Transcription initiation factor TFIID subunit 9B
16 - - 16.8
99
nuclear transcription factor Y subunit beta
16 - - 80.2
105
Inner kinetochore subunit cnp20
15 - - 78.5
104
Transcription initiation factor TFIID subunit 6
15 - - 76.7
106
Centromeric histone 3
15 - - 76.0
185
DNA-binding protein HMf-2
15
3D
 5t5kF00 - 17.4
107
Chromatin accessibility complex subunit 1
14 - - 22.1
110
Nuclear factor Y, subunit B1
14 - - 66.2
108
High mobility group protein B4, putative
14 - - 87.1
111
Histone H3
14 - - 51.9
109
Nuclear factor Y subunit C10
14 - - 91.4
112
Transcription initiation factor TFIID subunit 12
13 - - 17.8
128
Chromatin accessibility complex 14kD protein
13
3D
 2bymD00 - 87.2
113
Transcription initiation factor TFIID subunit 13
13 - - 24.2
114
Taf3p
13 - - 20.6
116
Transcription initiation factor TFIID subunit 8
12 - - 10.7
119
Unplaced genomic scaffold supercont1.244, whole genome shotgun sequence
11 - - 3.5
117
Nuclear factor Y, subunit C13
11 - - 62.5
118
Unplaced genomic scaffold supercont1.188, whole genome shotgun sequence
11 - - 5.1
120
Unplaced genomic scaffold supercont1.12, whole genome shotgun sequence
11 - - 3.3
126
Histone H2A
11
3D
 5chlB00 - 62.1
121
DNA polymerase II third subunit
11 - - 13.0
127
Bip2 protein
10 - - 13.6
122
CCAAT-HAP5 transcription factor
10 - - 89.2
125
Transcription initiation factor TFIID subunit 9
10 - - 10.8
129
Transcription factor TFIID complex subunit Taf13
10 - - 50.8
124
CCAAT-HAP3 transcription factor
10 - - 61.2
123
TAF
TBP-associated transcription factor
10 - - 58.5
136
Histone H2B
9 - - 31.7
130
Nuclear transcription factor Y subunit B-4
9 - - 55.3
132
CBF/NF-Y family transcription factor, putative
9 - - 53.0
135
Transcription initiation factor TFIID subunit 11
9 - - 4.1
131
Histone H2B
9 - - 76.2
133
Dls1p
9 - - 0.0
134
CCAAT-box DNA binding protein subunit B
9 - - 1.5
144
Conserved protein
8 - - 2.7
138
TAF
TBP-associated transcription factor
8 - - 49.2
137
DNA polymerase epsilon p12 subunit
8 - - 75.3
142
DNA polymerase epsilon subunit D
8 - - 2.7
140
Histone H3-like centromeric protein cse-4
8 - - 51.8
139
AaceriACL158Wp
8 - - 87.0
145
Chromatin accessibility complex protein 1-like Protein
8 - - 77.5
143
Uncharacterized protein
8 - - 20.2
141
Inner kinetochore subunit MHF2
8 - - 1.5
146
Histone H2A
8 - - 45.1
153
histone H3-like centromeric protein A isoform X2
7 - - 36.5
151
Uncharacterized protein
7 - - 2.4
155
H2A histone family member Y
7 - - 19.1
154
Transcription initiation factor tfiid, putative
7 - - 3.6
147
Histone H3, putative
7 - - 0.0
149
CBF/NF-Y transcription factor domain containing protein
7 - - 3.1
156
Centromere protein S
7 - - 87.4
152
CBF/NF-Y transcription factor family protein
7 - - 1.4
150
DR1
One
7 - - 22.1
148
Os07g0612500 protein
7 - - 10.2
157
Histone H3-like centromeric protein A
7 - - 53.8
160
Transcription initiation factor TFIID subunit, putative
6 - - 11.9
163
Histone H3, putative
6 - - 2.4
158
Histone-like_transcription_factor_
CBF/NF-Y
6 - - 77.7
161
Histone H3
6 - - 5.4
159
CBF/NF-Y family transcription factor, putative
6 - - 28.7
162
CBF/NF-Y transcription factor domain containing protein
6 - - 6.0
164
Uncharacterized protein
6 - - 18.3
177
Histone H3
5 - - 13.1
170
Histone H2A
5 - - 31.6
167
Histone H2A
5 - - 24.9
175
Uncharacterized protein
5 - - 7.1
165
Histone H2A
5 - - 74.5
173
Histone H2A
5 - - 43.1
168
Nuclear transcription factor Y subunit beta
5 - - 33.0
178
Histone H2B
5 - - 2.2
171
Histone H2B
5 - - 21.6
176
Histone H2B
5 - - 6.2
174
MIP14426p
5 - - 20.7
169
Histone H4
5 - - 21.1
172
Histone H2A
5 - - 39.6
179
Transcriptional activator hap3
5 - - 12.4
166
TAF
TBP-associated transcription factor
5 - - 87.9
180
Centromere protein W
4 - - 40.1
189
Uncharacterized protein
4 - - 6.6
191
4 - - 78.3
187
Uncharacterized protein
4 - - 4.8
182
DRAP1 corepressor homolog
4 - - 19.4
184
4 - - 19.3
181
4 - - 44.3
186
CCAAT-binding factor complex subunit Php3
4 - - 40.2
188
DNA polymerase epsilon subunit C, putative
4 - - 4.1
183
YALI0F17072p
4 - - 35.1
190
Histone H2A
4 - - 72.1
193
3 - - 32.2
205
3 - - 9.9
207
3 - - 0.0
198
3 - - 0.0
202
3 - - 11.9
196
3 - - 22.6
206
3 - - 7.2
194
3 - - 13.1
200
3 - - 3.1
197
3 - - 11.4
192
3 - - 17.9
199
3 - - 0.9
195
3 - - 38.8
201
3 - - 0.0
203
3 - - 7.5
204
3 - - 7.2
211
2 - - 37.7
236
2 - - 3.9
218
2 - - 25.9
234
2 - - 0.0
246
2 - - 2.6
221
2 - - 33.7
260
2 - - 0.0
262
2 - - 33.4
212
2 - - 42.3
227
2 - - 10.1
264
2 - - 28.1
255
2 - - 0.0
232
2 - - 4.9
225
2 - - 8.9
250
2 - - 0.0
257
2 - - 0.0
259
2 - - 0.0
249
2 - - 6.3
240
2 - - 0.0
230
2 - - 0.0
214
2 - - 20.8
229
2 - - 0.0
222
2 - - 37.1
217
2 - - 28.7
239
2 - - 0.0
269
2 - - 49.4
247
2 - - 0.0
209
2 - - 41.4
210
2 - - 8.7
252
2 - - 46.8
219
2 - - 32.7
242
2 - - 0.0
220
2 - - 31.8
226
2 - - 0.0
244
2 - - 0.0
237
2 - - 0.0
254
2 - - 0.0
235
2 - - 2.3
213
2 - - 42.8
265
2 - - 31.9
224
2 - - 0.0
251
2 - - 44.4
256
2 - - 0.0
263
2 - - 30.4
215
2 - - 20.6
245
2 - - 3.8
267
2 - - 40.9
233
2 - - 1.9
208
2 - - 11.6
241
2 - - 1.2
266
2 - - 41.8
243
2 - - 6.1
231
2 - - 0.0
261
2 - - 27.9
228
2 - - 12.1
268
2 - - 43.1
223
2 - - 0.0
238
2 - - 0.0
253
2 - - 0.0
216
2 - - 21.6
258
2 - - 10.8
248
2 - - 0.0
325
1 - - 0.0
378
1 - - 0.0
350
1 - - 0.0
337
1 - - 0.0
340
1 - - 0.0
311
1 - - 0.0
285
1 - - 0.0
288
1 - - 0.0
308
1 - - 0.0
373
1 - - 0.0
301
1 - - 0.0
366
1 - - 0.0
272
1 - - 0.0
287
1 - - 0.0
294
1 - - 0.0
349
1 - - 0.0
333
1 - - 0.0
323
1 - - 0.0
359
1 - - 0.0
330
1 - - 0.0
360
1 - - 0.0
274
1 - - 0.0
353
1 - - 0.0
375
1 - - 0.0
303
1 - - 0.0
278
1 - - 0.0
276
1 - - 0.0
347
1 - - 0.0
320
1 - - 0.0
361
1 - - 0.0
307
1 - - 0.0
326
1 - - 0.0
335
1 - - 0.0
299
1 - - 0.0
377
1 - - 0.0
315
1 - - 0.0
338
1 - - 0.0
305
1 - - 0.0
328
1 - - 0.0
281
1 - - 0.0
363
1 - - 0.0
317
1 - - 0.0
313
1 - - 0.0
284
1 - - 0.0
289
1 - - 0.0
319
1 - - 0.0
344
1 - - 0.0
357
1 - - 0.0
336
1 - - 0.0
297
1 - - 0.0
290
1 - - 0.0
365
1 - - 0.0
283
1 - - 0.0
271
1 - - 0.0
331
1 - - 0.0
358
1 - - 0.0
348
1 - - 0.0
364
1 - - 0.0
367
1 - - 0.0
324
1 - - 0.0
351
1 - - 0.0
379
1 - - 0.0
342
1 - - 0.0
295
1 - - 0.0
341
1 - - 0.0
312
1 - - 0.0
370
1 - - 0.0
309
1 - - 0.0
380
1 - - 0.0
300
1 - - 0.0
286
1 - - 0.0
296
1 - - 0.0
329
1 - - 0.0
275
1 - - 0.0
346
1 - - 0.0
352
1 - - 0.0
369
1 - - 0.0
279
1 - - 0.0
372
1 - - 0.0
293
1 - - 0.0
322
1 - - 0.0
310
1 - - 0.0
354
1 - - 0.0
332
1 - - 0.0
368
1 - - 0.0
316
1 - - 0.0
292
1 - - 0.0
291
1 - - 0.0
374
1 - - 0.0
327
1 - - 0.0
280
1 - - 0.0
273
1 - - 0.0
314
1 - - 0.0
355
1 - - 0.0
270
1 - - 0.0
334
1 - - 0.0
302
1 - - 0.0
362
1 - - 0.0
376
1 - - 0.0
298
1 - - 0.0
343
1 - - 0.0
321
1 - - 0.0
371
1 - - 0.0
339
1 - - 0.0
345
1 - - 0.0
282
1 - - 0.0
277
1 - - 0.0
304
1 - - 0.0
306
1 - - 0.0
318
1 - - 0.0
356
1 - - 0.0