The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Transcription Factor, Ets-1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
1406
3D
1b0xA00 - 91.1
2
1355
3D
3tadB02 - 76.0
3
967
3D
3tadB01 - 67.7
4
929
3D
3tadB03 - 91.0
5
878
3D
3tadD02 - 77.1
6
638
3D
2f44C00 - 90.6
7
612
3D
3tadD03 - 86.5
8
593
3D
2gleA00 - 97.0
9
571
3D
2k60A02 - 92.9
10
569
3D
1sxeA00 - 86.4
12
531
3D
5kniG00 - 90.9
11
530
3D
4pzoF00 - 75.6
13
474 - - 73.4
14
473
3D
2kmdA01 - 93.3
16
469
3D
2kivA01 - 68.7
15
468
3D
2kivA02 - 58.4
17
438 - - 76.8
18
424 - - 78.7
19
407
3D
3bs5B00 - 81.6
20
p63
373
3D
5n2oA00 - 80.4
21
350
3D
3bq7F00 - 79.3
22
334 - - 70.4
23
323
3D
2e8mA01 - 95.5
25
322
3D
4rqnC01 - 80.6
24
321 - - 76.3
26
292 - - 82.5
30
266
3D
2qb1B00 - 83.8
27
261 - - 47.0
29
259
3D
3kkaE00 - 89.7
28
259
3D
3senD01 - 89.6
32
224
3D
3senD02 - 81.4
31
218
3D
2lpeA02 - 94.7
33
218
3D
2fe9A00 - 85.8
34
199
3D
5f3xD00 - 97.0
35
3
188 - - 58.0
37
178 - - 87.9
36
178 - - 81.8
38
176
3D
2dl0A01 - 80.3
39
162
3D
1sxdA00 - 92.1
40
157
3D
2d8cA01 - 80.8
41
154 - - 66.1
42
153
3D
2dkzA01 - 50.4
43
149 - - 86.0
44
136 - - 74.4
45
130
3D
1v38A00 - 72.1
46
123 - - 81.6
49
122
3D
2ksoB00 - 52.2
50
121
3D
2dkxA00 - 87.2
47
121 - - 71.7
48
120 - - 60.0
51
119
3D
2eapA01 - 90.2
52
105 - - 78.0
53
103
3D
1v85A00 - 83.2
54
101 - - 73.0
55
96
3D
5zrzB00 - 95.4
56
94 - - 84.8
57
93
3D
2kg5A01 - 75.1
58
92
3D
1ucvA00 - 75.1
61
92
3D
1sv4B00 - 91.3
59
88 - - 74.3
60
86 - - 81.0
63
85
3D
2e8pA01 - 77.1
62
84 - - 81.3
64
74 - - 56.6
65
68 - - 80.5
66
62 - - 77.4
67
58
3D
2e8oA01 - 94.4
68
56 - - 58.2
69
55 - - 65.0
70
47 - - 40.1
71
43 - - 95.4
72
41 - - 23.2
73
41 - - 72.9
74
40 - - 93.3
75
37 - - 78.9
76
36
3D
1oxjA01 - 57.6
77
35 - - 87.7
78
SAM
34 - - 73.4
79
31 - - 60.0
80
31 - - 21.8
81
30 - - 66.1
82
26 - - 87.0
83
26 - - 75.7
84
Human endocytosis
25 - - 90.3
85
24 - - 14.9
86
24 - - 88.2
87
23 - - 86.2
89
22 - - 94.7
91
22
3D
5j8yD00 - 18.2
88
22 - - 54.8
90
21 - - 62.5
94
20
3D
3idwA00 - 73.4
92
20 - - 20.8
93
19 - - 67.0
95
18 - - 7.6
96
16 - - 61.9
98
16 - - 0.0
99
16 - - 16.9
97
16 - - 2.6
101
15 - - 64.8
100
15 - - 20.8
102
14 - - 23.6
103
14 - - 92.0
105
14
3D
3bs7B00 - 18.2
104
13 - - 46.1
107
AFU_orthologue AFUA_2G17130
11 - - 20.8
108
11 - - 22.0
115
11
3D
1x9xB00 - 0.0
106
11 - - 88.2
109
10 - - 0.0
110
10 - - 53.6
111
10 - - 83.6
113
9 - - 86.5
116
9 - - 76.1
112
9 - - 8.5
114
9 - - 29.6
118
8 - - 64.8
117
8 - - 6.8
119
7 - - 1.8
120
7 - - 21.9
121
7 - - 40.0
124
6 - - 74.2
126
6 - - 96.0
131
6
3D
1wwuA01 - 45.0
122
6 - - 11.9
125
6 - - 15.0
123
6 - - 23.1
127
5 - - 23.7
129
5 - - 86.6
128
5 - - 62.3
130
5 - - 16.1
132
5 - - 83.0
133
5 - - 87.7
134
5 - - 77.3
139
4 - - 13.4
135
4 - - 9.2
145
4 - - 15.9
136
4 - - 13.0
144
4 - - 11.3
138
ets domain transcription factor, epithelial-specific
4 - - 36.9
137
4 - - 4.7
142
4 - - 85.2
140
4 - - 14.2
143
4 - - 87.6
148
4 - - 77.8
147
4 - - 77.3
149
4 - - 59.0
141
4 - - 72.0
146
4 - - 85.7
153
3 - - 39.0
160
3 - - 0.0
152
3 - - 1.6
161
3 - - 0.0
151
3 - - 0.0
150
Sterile_alpha_motif
3 - - 7.1
155
3 - - 0.0
163
3 - - 64.9
154
3 - - 17.7
159
3 - - 11.0
162
3 - - 0.0
158
3 - - 0.0
157
3 - - 0.0
156
3 - - 4.7
164
3 - - 0.0
194
2 - - 1.3
168
2 - - 0.0
178
2 - - 45.1
193
2 - - 0.0
180
2 - - 46.4
189
2 - - 0.0
177
2 - - 24.4
171
2 - - 2.8
200
2 - - 1.8
197
2 - - 49.0
191
2 - - 0.0
187
2 - - 0.0
176
PTPRF liprin
2 - - 12.9
170
2 - - 10.4
182
2 - - 9.2
167
2 - - 9.3
192
2 - - 4.4
175
2 - - 7.3
199
EGR1 binding protein 1
2 - - 25.1
198
2 - - 46.0
184
2 - - 1.7
181
2 - - 0.0
195
2 - - 0.0
174
2 - - 0.0
188
2 - - 5.3
183
2 - - 0.0
169
2 - - 0.0
190
2 - - 0.0
165
2 - - 40.8
186
2 - - 1.7
172
2 - - 6.6
179
2 - - 49.5
173
2 - - 0.0
166
2 - - 0.0
185
2 - - 0.0
196
2 - - 41.2
206
1 - - 0.0
220
1 - - 0.0
226
1 - - 0.0
211
1 - - 0.0
236
1 - - 0.0
218
1 - - 0.0
234
1 - - 0.0
244
1 - - 0.0
246
1 - - 0.0
221
1 - - 0.0
237
1 - - 0.0
205
1 - - 0.0
235
1 - - 0.0
213
1 - - 0.0
224
1 - - 0.0
212
1 - - 0.0
227
1 - - 0.0
232
1 - - 0.0
225
1 - - 0.0
207
1 - - 0.0
215
1 - - 0.0
245
1 - - 0.0
233
1 - - 0.0
208
1 - - 0.0
241
1 - - 0.0
202
1 - - 0.0
240
1 - - 0.0
230
1 - - 0.0
201
1 - - 0.0
214
1 - - 0.0
229
1 - - 0.0
222
1 - - 0.0
217
1 - - 0.0
239
1 - - 0.0
243
1 - - 0.0
231
1 - - 0.0
203
1 - - 0.0
204
1 - - 0.0
228
1 - - 0.0
223
1 - - 0.0
238
1 - - 0.0
209
1 - - 0.0
216
1 - - 0.0
210
1 - - 0.0
219
1 - - 0.0
242
1 - - 0.0