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CATH Superfamily 1.10.10.1820

BsuBI/PstI restriction endonuclease, N-terminal domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
BsuBI/PstI restriction endonuclease-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: BsuBI/PstI restriction endonuclease, N-terminal domain

Type II restriction endonucleases are components of prokaryotic DNA restriction-modification mechanisms that protect the organism against invading foreign DNA. These site-specific deoxyribonucleases catalyse the endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates PMID:15770420. This superfamily represents the N-terminal domain of bacterial enzymes similar to type II restriction endonucleases BsuBI and PstI. The structure contains a winged-helix-turn-helix DNA binding structure. The enzymes of the BsuBI restriction/modification (R/M) system recognise the target sequence 5'CTGCAG and are functionally identical with those of the PstI R/M system PMID:1480472. PMID:15770420 PMID:1480472

GO Diversity

Unique GO annotations
3 Unique GO terms

EC Diversity

Unique EC annotations
1 Unique EC terms

Species Diversity

Unique species annotations
527 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 2
Domain clusters (>95% seq id): 1
Domain clusters (>35% seq id): 1
Unique PDBs: 1
Alignments
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 1
Function
Unique EC: 1
Unique GO: 3
Taxonomy
Unique Species: 527
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