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CATH Superfamily 1.10.10.1050

Dcp2, box A domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Dcp2, box A domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Dcp2, box A domain

This superfamily represents the box A domain specific to mRNA decapping protein 2, Dcp2, the catalytic subunit of the mRNA-decapping enzyme PMID:12218187. Removal of the cap structure is mediated by the Dcp1-Dcp2 complex. This domain is found at the N-terminus of the NUDIX hydrolase domain (INTERPRO:IPR000086, PFAM:PF00293).

PFAM:PF05026,INTERPRO:IPR007722

GO Diversity

Unique GO annotations
50 Unique GO terms

EC Diversity

Unique EC annotations
1 Unique EC terms

Species Diversity

Unique species annotations
1388 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 7
Domain clusters (>95% seq id): 3
Domain clusters (>35% seq id): 2
Unique PDBs: 3
Alignments
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 24
Function
Unique EC: 1
Unique GO: 50
Taxonomy
Unique Species: 1388