CATH Domain 6qfyA00

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.60	Sandwich
	2.60.120	Jelly Rolls
	2.60.120.960	Spike glycoprotein, N-terminal domain

Domain Context

CATH Clusters

Superfamily	Spike glycoprotein, N-terminal domain
Functional Family	Spike glycoprotein

Enzyme Information

UniProtKB Entries (1)

A0A1Z2WUW0_9BETC

Porcine hemagglutinating encephalomyelitis virus

Spike glycoprotein

PDB Structure

PDB	6QFY
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Human coronaviruses OC43 and HKU1 bind to 9-O-acetylated sialic acids via a conserved receptor-binding site in spike protein domain A. Hulswit, R.J.G., Lang, Y., Bakkers, M.J.G., Li, W., Li, Z., Schouten, A., Ophorst, B., van Kuppeveld, F.J.M., Boons, G.J., Bosch, B.J., Huizinga, E.G., de Groot, R.J. Proc. Natl. Acad. Sci. U.S.A.