CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphorylase Kinase; domain 1
Functional Family serine/threonine-protein kinase TBK1 isoform X1

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt Q9UHD2
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (2)

E1C7U0
STING_CHICK
Gallus gallus
Stimulator of interferon genes protein
Q9UHD2
TBK1_HUMAN
Homo sapiens
Serine/threonine-protein kinase TBK1

PDB Structure

PDB 6NT9
External Links
Method ELECTRON MICROSCOPY
Organism
Primary Citation
Structural basis of STING binding with and phosphorylation by TBK1.
Zhang, C., Shang, G., Gui, X., Zhang, X., Bai, X.C., Chen, Z.J.
Nature