CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphorylase Kinase; domain 1
Functional Family Tyrosine-protein kinase

Enzyme Information

UniProtKB Entries (1)

Q7TMU1
Q7TMU1_MOUSE
Mus musculus
Tyrosine-protein kinase

PDB Structure

PDB 6MNY
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Aminopyrazole Carboxamide Bruton's Tyrosine Kinase Inhibitors. Irreversible to Reversible Covalent Reactive Group Tuning.
Schnute, M.E., Benoit, S.E., Buchler, I.P., Caspers, N., Grapperhaus, M.L., Han, S., Hotchandani, R., Huang, N., Hughes, R.O., Juba, B.M., Kim, K.H., Liu, E., McCarthy, E., Messing, D., Miyashiro, J.S., Mohan, S., O'Connell, T.N., Ohren, J.F., Parikh, M.D., Schmidt, M., Selness, S.R., Springer, J.R., Thanabal, V., Trujillo, J.I., Walker, D.P., Wan, Z.K., Withka, J.M., Wittwer, A.J., Wood, N.L., Xing, L., Zapf, C.W., Douhan III, J.
ACS Med Chem Lett