CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.60 | Sandwich |
|
2.60.40 | Immunoglobulin-like |
|
2.60.40.150 | C2 domain |
Domain Context
CATH Clusters
| Superfamily | C2 domain |
| Functional Family | Phospholipase A2 |
Enzyme Information
| 3.1.1.4 |
Phospholipase A(2).
based on mapping to UniProt P49147
Phosphatidylcholine + H(2)O = 1-acylglycerophosphocholine + a carboxylate.
-!- Also acts on phosphatidylethanolamine, choline plasmalogen and phosphatides, removing the fatty acid attached to the 2-position.
|
| 3.1.1.5 |
Lysophospholipase.
based on mapping to UniProt P49147
2-lysophosphatidylcholine + H(2)O = glycerophosphocholine + a carboxylate.
|
UniProtKB Entries (1)
| P49147 |
PA24A_CHICK
Gallus gallus
Cytosolic phospholipase A2
|
PDB Structure
| PDB | 6IEJ |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural basis of phosphatidylcholine recognition by the C2-domain of cytosolic phospholipase A2alpha.
Elife
|