CATH Classification

Domain Context

CATH Clusters

Superfamily 2.80.10.50
Functional Family Fascin

Enzyme Information

UniProtKB Entries (1)

Q16658
FSCN1_HUMAN
Homo sapiens
Fascin

PDB Structure

PDB 6I17
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure-based design, synthesis and biological evaluation of a novel series of isoquinolone and pyrazolo[4,3-c]pyridine inhibitors of fascin 1 as potential anti-metastatic agents.
Francis, S., Croft, D., Schuttelkopf, A.W., Parry, C., Pugliese, A., Cameron, K., Claydon, S., Drysdale, M., Gardner, C., Gohlke, A., Goodwin, G., Gray, C.H., Konczal, J., McDonald, L., Mezna, M., Pannifer, A., Paul, N.R., Machesky, L., McKinnon, H., Bower, J.
Bioorg.Med.Chem.Lett.