CATH Classification

Domain Context

CATH Clusters

Superfamily alpha/beta hydrolase
Functional Family Acetylcholinesterase

Enzyme Information

3.1.1.7
Acetylcholinesterase.
based on mapping to UniProt P04058
Acetylcholine + H(2)O = choline + acetate.
-!- Acts on a variety of acetic esters. -!- Also catalyzes transacetylations.

UniProtKB Entries (1)

P04058
ACES_TETCF
Tetronarce californica
Acetylcholinesterase

PDB Structure

PDB 6H12
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Design, biological evaluation and X-ray crystallography of nanomolar multifunctional ligands targeting simultaneously acetylcholinesterase and glycogen synthase kinase-3.
Oukoloff, K., Coquelle, N., Bartolini, M., Naldi, M., Le Guevel, R., Bach, S., Josselin, B., Ruchaud, S., Catto, M., Pisani, L., Denora, N., Iacobazzi, R.M., Silman, I., Sussman, J.L., Buron, F., Colletier, J.P., Jean, L., Routier, S., Renard, P.Y.
Eur.J.Med.Chem.