CATH Classification

Domain Context

CATH Clusters

Superfamily Microbial ribonucleases
Functional Family Guanyl-specific ribonuclease T1

Enzyme Information

3.1.27.3
Ribonuclease T(1).
based on mapping to UniProt P00651
Two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides ending in G-P with 2',3'-cyclic phosphate intermediates.
-!- Formerly EC 2.7.7.26 and EC 3.1.4.8.

UniProtKB Entries (1)

P00651
RNT1_ASPOR
Aspergillus oryzae RIB40
Guanyl-specific ribonuclease T1

PDB Structure

PDB 6GSP
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Hydrolysis of a slow cyclic thiophosphate substrate of RNase T1 analyzed by time-resolved crystallography.
Zegers, I., Loris, R., Dehollander, G., Fattah Haikal, A., Poortmans, F., Steyaert, J., Wyns, L.
Nat.Struct.Biol.