1 keywords

CATH Domain 6gntA00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.630 Aminopeptidase
Homologous Superfamily 3.40.630.170  

Domain Context

CATH Clusters

Superfamily 3.40.630.170
Functional Family Glycylpeptide N-tetradecanoyltransferase

Enzyme Information

UniProtKB Entries (1)

Q4Q5S8
Q4Q5S8_LEIMA
Leishmania major
Glycylpeptide N-tetradecanoyltransferase

PDB Structure

PDB 6GNT
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A Molecular Hybridization Approach for the Design of Potent, Highly Selective, and Brain-Penetrant N-Myristoyltransferase Inhibitors.
Harrison, J.R., Brand, S., Smith, V., Robinson, D.A., Thompson, S., Smith, A., Davies, K., Mok, N., Torrie, L.S., Collie, I., Hallyburton, I., Norval, S., Simeons, F.R.C., Stojanovski, L., Frearson, J.A., Brenk, R., Wyatt, P.G., Gilbert, I.H., Read, K.D.
J. Med. Chem.