CATH Classification

Domain Context

CATH Clusters

Superfamily Ubiquinol cytochrome reductase, transmembrane domain
Functional Family Cytochrome b-c1 complex subunit Rieske, mitochondrial

Enzyme Information

7.1.1.8
Quinol--cytochrome-c reductase.
based on mapping to UniProt P08067
Quinol + 2 ferricytochrome c(Side 2) = quinone + 2 ferrocytochrome c(Side 2) + 2 H(+)(Side 2).
-!- The enzyme, often referred to as the cytochrome bc1 complex or complex III, is the third complex in the electron transport chain. -!- It is present in the mitochondria of all aerobic eukaryotes and in the inner membranes of most bacteria. -!- The mammalian enzyme contains cytochromes b-562, b-566 and c(1), and a 2-iron ferredoxin. -!- Depending on the organism and physiological conditions, the enzyme extrudes either two or four protons from the cytoplasmic to the non- cytoplasmic compartment (cf. EC 1.6.99.3). -!- Formerly EC 1.10.2.2.

UniProtKB Entries (1)

P08525
QCR8_YEAST
Saccharomyces cerevisiae S288C
Cytochrome b-c1 complex subunit 8

PDB Structure

PDB 6GIQ
External Links
Method ELECTRON MICROSCOPY
Organism
Primary Citation
Cryo-EM structure of the yeast respiratory supercomplex.
Rathore, S., Berndtsson, J., Marin-Buera, L., Conrad, J., Carroni, M., Brzezinski, P., Ott, M.
Nat. Struct. Mol. Biol.