CATH Classification

Domain Context

CATH Clusters

Superfamily Cupredoxins - blue copper proteins
Functional Family

Enzyme Information

1.7.2.1
Nitrite reductase (NO-forming).
based on mapping to UniProt P25006
Nitric oxide + H(2)O + ferricytochrome c = nitrite + ferrocytochrome c + 2 H(+).
-!- The reaction is catalyzed by two types of enzymes, found in the perimplasm of denitrifying bacteria. -!- One type comprises proteins containing multiple copper centers, the other a heme protein, cytochrome cd1. -!- Acceptors include c-type cytochromes such as cytochrome c-550 or cytochrome c-551 from Paracoccus denitrificans or Pseudomonas aeruginosa, and small blue copper proteins such as azurin and pseudoazurin. -!- Cytochrome cd1 also has oxidase and hydroxylamine reductase activities. -!- May also catalyze the reaction of EC 1.7.99.1 since this is a well- known activity of cytochrome cd1. -!- Formerly EC 1.6.6.5, EC 1.7.99.3 and EC 1.9.3.2.

UniProtKB Entries (1)

P25006
NIR_ACHCY
Achromobacter cycloclastes
Copper-containing nitrite reductase

PDB Structure

PDB 6GBY
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Resolving polymorphs and radiation-driven effects in microcrystals using fixed-target serial synchrotron crystallography.
Ebrahim, A., Appleby, M.V., Axford, D., Beale, J., Moreno-Chicano, T., Sherrell, D.A., Strange, R.W., Hough, M.A., Owen, R.L.
Acta Crystallogr D Struct Biol