CATH Classification

Domain Context

CATH Clusters

Superfamily Cytochrome-c3 Hydrogenase, chain B
Functional Family Hydrogenase 2 large subunit

Enzyme Information

1.12.99.6
Hydrogenase (acceptor).
based on mapping to UniProt P0ACD8
H(2) + A = AH(2).
-!- Uses molecular hydrogen for the reduction of a variety of substances.

UniProtKB Entries (3)

P0ACD8
MBHL_ECOLI
Escherichia coli K-12
Hydrogenase-1 large chain
P69740
MBHS_ECOL6
Escherichia coli CFT073
Hydrogenase-1 small chain
P0AAM2
CYBH_ECO57
Escherichia coli O157:H7
Probable Ni/Fe-hydrogenase 1 B-type cytochrome subunit

PDB Structure

PDB 6G94
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
X-ray structural, functional and computational studies of the O2-sensitive E. coli hydrogenase-1 C19G variant reveal an unusual [4Fe-4S] cluster.
Volbeda, A., Mouesca, J.M., Darnault, C., Roessler, M.M., Parkin, A., Armstrong, F.A., Fontecilla-Camps, J.C.
Chem. Commun. (Camb.)