CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.170 | Beta Complex |
|
2.170.16 | Endonuclease - Pi-scei; Chain A, domain 1 |
|
2.170.16.10 | Hedgehog/Intein (Hint) domain |
Domain Context
CATH Clusters
| Superfamily | Hedgehog/Intein (Hint) domain |
| Functional Family |
Enzyme Information
| 3.6.4.12 |
DNA helicase.
based on mapping to UniProt Q55418
ATP + H(2)O = ADP + phosphate.
-!- DNA helicases utilize the energy from ATP hydrolysis to unwind double-stranded DNA. -!- Some of them unwind duplex DNA with a 3' to 5' polarity (1,3,5,8), other show 5' to 3' polarity (10,11,12,13) or unwind DNA in both directions (14,15). -!- Some helicases unwind DNA as well as RNA (4,9). -!- May be identical with EC 3.6.4.13 (RNA helicase).
|
UniProtKB Entries (1)
| Q55418 |
DNAB_SYNY3
Synechocystis sp. PCC 6803 substr. Kazusa
Replicative DNA helicase
|
PDB Structure
| PDB | 6FRH |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
A functional interplay between intein and extein sequences in protein splicing compensates for the essential block B histidine.
Chem Sci
|