CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.150 | Vaccinia Virus protein VP39 |
Domain Context
CATH Clusters
| Superfamily | Vaccinia Virus protein VP39 |
| Functional Family |
Enzyme Information
| 2.1.1.44 |
L-histidine N(alpha)-methyltransferase.
based on mapping to UniProt A0R5M8
3 S-adenosyl-L-methionine + L-histidine = 3 S-adenosyl-L-homocysteine + hercynine.
-!- Part of the biosynthetic pathway of ergothioneine.
|
UniProtKB Entries (1)
| A0R5M8 |
EGTD_MYCS2
Mycolicibacterium smegmatis MC2 155
Histidine N-alpha-methyltransferase
|
PDB Structure
| PDB | 6FNT |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Inhibition and Regulation of the Ergothioneine Biosynthetic Methyltransferase EgtD.
ACS Chem. Biol.
|