CATH Classification

Domain Context

CATH Clusters

Superfamily Imidazole glycerol phosphate dehydratase; domain 1
Functional Family Imidazoleglycerol-phosphate dehydratase HisB

Enzyme Information

4.2.1.19
Imidazoleglycerol-phosphate dehydratase.
based on mapping to UniProt O23346
D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2- oxopropyl phosphate + H(2)O.

UniProtKB Entries (1)

O23346
HIS5B_ARATH
Arabidopsis thaliana
Imidazoleglycerol-phosphate dehydratase 2, chloroplastic

PDB Structure

PDB 6EZJ
External Links
Method ELECTRON MICROSCOPY
Organism
Primary Citation
Elucidating the structural basis for differing enzyme inhibitor potency by cryo-EM.
Rawson, S., Bisson, C., Hurdiss, D.L., Fazal, A., McPhillie, M.J., Sedelnikova, S.E., Baker, P.J., Rice, D.W., Muench, S.P.
Proc. Natl. Acad. Sci. U.S.A.