CATH Domain 6exmB02

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.10	Arc Repressor Mutant, subunit A
	1.10.10.10	Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain

Domain Context

CATH Clusters

Superfamily	Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
Functional Family	Listeriolysin regulatory protein

Enzyme Information

UniProtKB Entries (1)

PRFA_LISMO

Listeria monocytogenes EGD-e

Listeriolysin regulatory protein

PDB Structure

PDB	6EXM
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structure-Based Design of Inhibitors Targeting PrfA, the Master Virulence Regulator of Listeria monocytogenes. Kulen, M., Lindgren, M., Hansen, S., Cairns, A.G., Grundstrom, C., Begum, A., van der Lingen, I., Brannstrom, K., Hall, M., Sauer, U.H., Johansson, J., Sauer-Eriksson, A.E., Almqvist, F. J. Med. Chem.