CATH Domain 6erhC03

CATH Classification

Level	CATH Code	Description
	4	Few Secondary Structures
	4.10	Irregular
	4.10.970	Ku70, bridge and pillars
	4.10.970.10	Ku70, bridge and pillars

Domain Context

CATH Clusters

Superfamily	Ku70, bridge and pillars
Functional Family	X-ray repair cross-complementing protein 6 isoform X1

Enzyme Information

4.2.99.-	Other carbon-oxygen lyases. based on mapping to UniProt P12956
3.6.4.-	Acting on ATP; involved in cellular and subcellular movement. based on mapping to UniProt P12956

UniProtKB Entries (1)

NHEJ1_HUMAN

Homo sapiens

Non-homologous end-joining factor 1

PDB Structure

PDB	6ERH
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining. Nemoz, C., Ropars, V., Frit, P., Gontier, A., Drevet, P., Yu, J., Guerois, R., Pitois, A., Comte, A., Delteil, C., Barboule, N., Legrand, P., Baconnais, S., Yin, Y., Tadi, S., Barbet-Massin, E., Berger, I., Le Cam, E., Modesti, M., Rothenberg, E., Calsou, P., Charbonnier, J.B. Nat. Struct. Mol. Biol.