CATH Classification

Domain Context

CATH Clusters

Superfamily 1.10.1600.10
Functional Family X-ray repair cross-complementing protein 6 isoform X2

Enzyme Information

4.2.99.-
Other carbon-oxygen lyases.
based on mapping to UniProt P12956
3.6.4.-
Acting on ATP; involved in cellular and subcellular movement.
based on mapping to UniProt P12956

UniProtKB Entries (1)

Q9H9Q4
NHEJ1_HUMAN
Homo sapiens
Non-homologous end-joining factor 1

PDB Structure

PDB 6ERH
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining.
Nemoz, C., Ropars, V., Frit, P., Gontier, A., Drevet, P., Yu, J., Guerois, R., Pitois, A., Comte, A., Delteil, C., Barboule, N., Legrand, P., Baconnais, S., Yin, Y., Tadi, S., Barbet-Massin, E., Berger, I., Le Cam, E., Modesti, M., Rothenberg, E., Calsou, P., Charbonnier, J.B.
Nat. Struct. Mol. Biol.