CATH Domain 6er5A03

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.390	Enolase-like; domain 1
	3.30.390.30	FAD/NAD-linked reductase, C-terminal dimerisation domain

Domain Context

CATH Clusters

Superfamily	3.30.390.30
Functional Family	Trypanothione reductase

Enzyme Information

UniProtKB Entries (1)

A4HSF7_LEIIN

Leishmania infantum

Trypanothione reductase

PDB Structure

PDB	6ER5
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Identification and binding mode of a novel Leishmania Trypanothione reductase inhibitor from high throughput screening. Turcano, L., Torrente, E., Missineo, A., Andreini, M., Gramiccia, M., Di Muccio, T., Genovese, I., Fiorillo, A., Harper, S., Bresciani, A., Colotti, G., Ilari, A. Plos Negl Trop Dis