1 keywords

CATH Domain 6djjA01

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.30 2-Layer Sandwich
Topology 3.30.870 Endonuclease; Chain A
Homologous Superfamily 3.30.870.10 Endonuclease Chain A

Domain Context

CATH Clusters

Superfamily Endonuclease Chain A
Functional Family Tyrosyl-DNA phosphodiesterase 1

Enzyme Information

UniProtKB Entries (0)

PDB Structure

PDB 6DJJ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Identification of a ligand binding hot spot and structural motifs replicating aspects of tyrosyl-DNA phosphodiesterase I (TDP1) phosphoryl recognition by crystallographic fragment cocktail screening.
Lountos, G.T., Zhao, X.Z., Kiselev, E., Tropea, J.E., Needle, D., Pommier, Y., Burke, T.R., Waugh, D.S.
Nucleic Acids Res.