CATH Domain 6dfnA00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.565	Retinoid X Receptor
	1.10.565.10	Retinoid X Receptor

Domain Context

CATH Clusters

Superfamily	Retinoid X Receptor
Functional Family	Estrogen receptor

Enzyme Information

UniProtKB Entries (1)

ESR1_HUMAN

Homo sapiens

Estrogen receptor

PDB Structure

PDB	6DFN
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Unexpected equivalent potency of a constrained chromene enantiomeric pair rationalized by co-crystal structures in complex with estrogen receptor alpha. Zhang, B., Kiefer, J.R., Blake, R.A., Chang, J.H., Hartman, S., Ingalla, E.R., Kleinheinz, T., Mody, V., Nannini, M., Ortwine, D.F., Ran, Y., Sambrone, A., Sampath, D., Vinogradova, M., Zhong, Y., Nwachukwu, J.C., Nettles, K.W., Lai, T., Liao, J., Zheng, X., Chen, H., Wang, X., Liang, J. Bioorg. Med. Chem. Lett.