CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.555 | Phosphatidylinositol 3-kinase; Chain A |
|
1.10.555.10 | Rho GTPase activation protein |
Domain Context
CATH Clusters
| Superfamily | Rho GTPase activation protein |
| Functional Family | Phosphatidylinositol 3-kinase regulatory subunit alpha |
Enzyme Information
UniProtKB Entries (1)
| P23727 |
P85A_BOVIN
Bos taurus
Phosphatidylinositol 3-kinase regulatory subunit alpha
|
PDB Structure
| PDB | 6D85 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Patient-derived mutations within the N-terminal domains of p85 alpha impact PTEN or Rab5 binding and regulation.
Sci Rep
|