CATH Domain 6d3mF00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.60	4-Layer Sandwich
	3.60.130	Double-stranded beta-helix
	3.60.130.10	Clavaminate synthase-like

Domain Context

CATH Clusters

Superfamily	Clavaminate synthase-like
Functional Family

Enzyme Information

1.14.11.44

(R)-dichlorprop dioxygenase (2-oxoglutarate).

based on mapping to UniProt Q8KSC8

(1) (R)-2-(4-chloro-2-methylphenoxy)propanoate + 2-oxoglutarate + O(2) = 4-chloro-2-methylphenol + pyruvate + succinate + CO(2). (2) (R)-(2,4-dichlorophenoxy)propanoate + 2-oxoglutarate + O(2) = 2,4- dichlorophenol + pyruvate + succinate + CO(2).

-!- The enzymes from the Gram-negative bacteria Delftia acidovorans MC1 and Sphingomonas herbicidovorans MH are involved in the degradation of the (R)-enantiomer of the phenoxyalkanoic acid herbicides mecoprop and dichlorprop.

UniProtKB Entries (1)

Q8KSC8

RDPA_SPHHM

Sphingobium herbicidovorans NBRC 16415

(R)-phenoxypropionate/alpha-ketoglutarate-dioxygenase

PDB Structure

PDB	6D3M
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Development of enzymes for robust aryloxyphenoxypropionate and synthetic auxin herbicide tolerance traits in maize and soybean crops. Larue, C.T., Goley, M., Shi, L., Evdokimov, A.G., Sparks, O.C., Ellis, C., Wollacott, A.M., Rydel, T.J., Halls, C.E., Van Scoyoc, B., Fu, X., Nageotte, J.R., Adio, A.M., Zheng, M., Sturman, E.J., Garvey, G.S., Varagona, M.J. Pest Manag. Sci.