CATH Classification

Domain Context

CATH Clusters

Superfamily Fructose-1,6-Bisphosphatase, subunit A, domain 1
Functional Family

Enzyme Information

3.1.3.25
Inositol-phosphate phosphatase.
based on mapping to UniProt O30298
Myo-inositol phosphate + H(2)O = myo-inositol + phosphate.
-!- Acts on five of the six isomers of myo-inositol phosphate, all except myo-inositol 2-phosphate, but does not act on myo-inositol bearing more than one phosphate group. -!- It also acts on adenosine 2'-phosphate (but not the 3'- or 5'-phosphates), sn-glycerol 3-phosphate and glycerol 2-phosphate, but does not act on inositol bisphosphates or more phosphorylated inositols.
3.1.3.11
Fructose-bisphosphatase.
based on mapping to UniProt O30298
D-fructose 1,6-bisphosphate + H(2)O = D-fructose 6-phosphate + phosphate.
-!- The animal enzyme also acts on sedoheptulose 1,7-bisphosphate.

UniProtKB Entries (1)

O30298
BSUHB_ARCFU
Archaeoglobus fulgidus DSM 4304
Fructose-1,6-bisphosphatase/inositol-1-monophosphatase

PDB Structure

PDB 6B63
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Osmolyte binding capacity of a dual action IMPase/FBPase (AF2372)
Goldstein, R.I., Roberts, M.
To Be Published