CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.10210 | Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (CobT), large domain |
Domain Context
CATH Clusters
| Superfamily | 3.40.50.10210 |
| Functional Family | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase |
Enzyme Information
| 2.4.2.21 |
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase.
based on mapping to UniProt A1JTP8
Beta-nicotinate D-ribonucleotide + 5,6-dimethylbenzimidazole = nicotinate + alpha-ribazole 5'-phosphate.
-!- Also acts on benzimidazole, and the clostridial enzyme acts on adenine to form 7-alpha-D-ribosyladenine 5'-phosphate. -!- The product of the reaction, alpha-ribazole 5'-phosphate, forms part of the corrin biosynthesis pathway and is a substrate for EC 2.7.8.2. -!- It can also be dephosphorylated to form alpha-ribazole by the action of EC 3.1.3.73.
|
UniProtKB Entries (1)
| A1JTP8 |
COBT_YERE8
Yersinia enterocolitica subsp. enterocolitica 8081
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase
|
PDB Structure
| PDB | 6B5F |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structure of nicotinate mononucleotide-5,6-dimethylbenzimidazole phosphoribosyltransferase CobT from Yersinia enterocolitica
To Be Published
|