CATH Classification

Domain Context

CATH Clusters

Superfamily Cytochrome P450
Functional Family

Enzyme Information

UniProtKB Entries (1)

A0A2H4A2U9
A0A2H4A2U9_NAEFO
Naegleria fowleri
CYP51, sterol 14alpha-demethylase

PDB Structure

PDB 6AYC
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
CYP51 is an essential drug target for the treatment of primary amoebic meningoencephalitis (PAM).
Debnath, A., Calvet, C.M., Jennings, G., Zhou, W., Aksenov, A., Luth, M.R., Abagyan, R., Nes, W.D., McKerrow, J.H., Podust, L.M.
PLoS Negl Trop Dis
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