CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.1270 | Trp Operon Repressor; Chain A |
|
1.10.1270.20 | tRNA(m1g37)methyltransferase, domain 2 |
Domain Context
CATH Clusters
| Superfamily | tRNA(m1g37)methyltransferase, domain 2 |
| Functional Family | tRNA (guanine-N(1)-)-methyltransferase |
Enzyme Information
UniProtKB Entries (0)
PDB Structure
| PDB | 5ZHN |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Thienopyrimidinone Derivatives That Inhibit Bacterial tRNA (Guanine37-N1)-Methyltransferase (TrmD) by Restructuring the Active Site with a Tyrosine-Flipping Mechanism.
J.Med.Chem.
|