CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.150 | Vaccinia Virus protein VP39 |
Domain Context
CATH Clusters
| Superfamily | Vaccinia Virus protein VP39 |
| Functional Family | Phenylethanolamine N-methyltransferase |
Enzyme Information
| 2.1.1.1 |
Nicotinamide N-methyltransferase.
based on mapping to UniProt P40261
S-adenosyl-L-methionine + nicotinamide = S-adenosyl-L-homocysteine + 1-methylnicotinamide.
|
UniProtKB Entries (1)
| P40261 |
NNMT_HUMAN
Homo sapiens
Nicotinamide N-methyltransferase
|
PDB Structure
| PDB | 5YJF |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
A small molecule inhibitor of Nicotinamide N-methyltransferase for the treatment of metabolic disorders.
Sci Rep
|
