CATH Domain 5y27A00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.20	Histone, subunit A
	1.10.20.10	Histone, subunit A

Domain Context

CATH Clusters

Superfamily	Histone, subunit A
Functional Family

Enzyme Information

2.7.7.7

DNA-directed DNA polymerase.

based on mapping to UniProt P87174

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).

-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.

UniProtKB Entries (1)

P87174

DPB4_SCHPO

Schizosaccharomyces pombe 972h-

DNA polymerase epsilon subunit D

PDB Structure

PDB	5Y27
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Coordinated regulation of heterochromatin inheritance by Dpb3-Dpb4 complex. He, H., Li, Y., Dong, Q., Chang, A.Y., Gao, F., Chi, Z., Su, M., Zhang, F., Ban, H., Martienssen, R., Chen, Y.H., Li, F. Proc. Natl. Acad. Sci. U.S.A.