CATH Domain 5wmtB00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.565	Heat Shock Protein 90
	3.30.565.10	Histidine kinase-like ATPase, C-terminal domain

Domain Context

CATH Clusters

Superfamily	Histidine kinase-like ATPase, C-terminal domain
Functional Family	Heat shock protein 90

Enzyme Information

UniProtKB Entries (1)

ENPL_CANLF

Canis lupus familiaris

Endoplasmin

PDB Structure

PDB	5WMT
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structure Based Design of a Grp94-Selective Inhibitor: Exploiting a Key Residue in Grp94 To Optimize Paralog-Selective Binding. Que, N.L.S., Crowley, V.M., Duerfeldt, A.S., Zhao, J., Kent, C.N., Blagg, B.S.J., Gewirth, D.T. J. Med. Chem.