CATH Classification

Domain Context

CATH Clusters

Superfamily SET domain
Functional Family Euchromatic histone-lysine N-methyltransferase 2

Enzyme Information

2.1.1.43
Histone-lysine N-methyltransferase.
based on mapping to UniProt Q96KQ7
S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].
2.1.1.-
Methyltransferases.
based on mapping to UniProt Q96KQ7

UniProtKB Entries (1)

Q96KQ7
EHMT2_HUMAN
Homo sapiens
Histone-lysine N-methyltransferase EHMT2

PDB Structure

PDB 5VSC
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure-activity relationship studies of G9a-like protein (GLP) inhibitors.
Xiong, Y., Li, F., Babault, N., Wu, H., Dong, A., Zeng, H., Chen, X., Arrowsmith, C.H., Brown, P.J., Liu, J., Vedadi, M., Jin, J.
Bioorg. Med. Chem.