CATH Classification

Domain Context

CATH Clusters

Superfamily 1.10.10.1780
Functional Family Toxin B

Enzyme Information

UniProtKB Entries (2)

C9YJ35
C9YJ35_PEPDR
Clostridioides difficile R20291
Toxin B
S6B291
S6B291_HUMAN
Homo sapiens
IgG H chain

PDB Structure

PDB 5VQM
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A neutralizing antibody that blocks delivery of the enzymatic cargo of Clostridium difficile toxin TcdB into host cells.
Kroh, H.K., Chandrasekaran, R., Zhang, Z., Rosenthal, K., Woods, R., Jin, X., Nyborg, A.C., Rainey, G.J., Warrener, P., Melnyk, R.A., Spiller, B.W., Lacy, D.B.
J. Biol. Chem.