1 keywords

CATH Domain 5vmrB02

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.80 Trefoil
Topology 2.80.10 Trefoil (Acidic Fibroblast Growth Factor, subunit A)
Homologous Superfamily 2.80.10.50  

Domain Context

CATH Clusters

Superfamily 2.80.10.50
Functional Family

Enzyme Information

3.4.24.69
Bontoxilysin.
based on mapping to UniProt P10844
Limited hydrolysis of proteins of the neuroexocytosis apparatus, synaptobrevins, SNAP25 or syntaxin. No detected action on small molecule substrates.
-!- Belongs to peptidase family M27.

UniProtKB Entries (1)

P10844
BXB_CLOBO
Clostridium botulinum
Botulinum neurotoxin type B

PDB Structure

PDB 5VMR
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Massively parallel de novo protein design for targeted therapeutics.
Chevalier, A., Silva, D.A., Rocklin, G.J., Hicks, D.R., Vergara, R., Murapa, P., Bernard, S.M., Zhang, L., Lam, K.H., Yao, G., Bahl, C.D., Miyashita, S.I., Goreshnik, I., Fuller, J.T., Koday, M.T., Jenkins, C.M., Colvin, T., Carter, L., Bohn, A., Bryan, C.M., Fernandez-Velasco, D.A., Stewart, L., Dong, M., Huang, X., Jin, R., Wilson, I.A., Fuller, D.H., Baker, D.
Nature