CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.565 | Retinoid X Receptor |
|
1.10.565.10 | Retinoid X Receptor |
Domain Context
CATH Clusters
| Superfamily | Retinoid X Receptor |
| Functional Family | Androgen receptor variant |
Enzyme Information
UniProtKB Entries (1)
| P10275 |
ANDR_HUMAN
Homo sapiens
Androgen receptor
|
PDB Structure
| PDB | 5V8Q |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Synthesis and biological evaluation of novel selective androgen receptor modulators (SARMs) Part III: Discovery of 4-(5-oxopyrrolidine-1-yl)benzonitrile derivative 2f as a clinical candidate.
Bioorg. Med. Chem.
|