1 keywords

CATH Domain 5v02B00

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.10 Orthogonal Bundle
Topology 1.10.287 Helix Hairpins
Homologous Superfamily 1.10.287.70  

Domain Context

CATH Clusters

Superfamily 1.10.287.70
Functional Family Small conductance calcium-activated potassium channel, isoform O

Enzyme Information

UniProtKB Entries (1)

Q9H2S1
KCNN2_HUMAN
Homo sapiens
Small conductance calcium-activated potassium channel protein 2

PDB Structure

PDB 5V02
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
An Intracellular Allosteric Modulator Binding Pocket in SK2 Ion Channels Is Shared by Multiple Chemotypes.
Cho, L.T., Alexandrou, A.J., Torella, R., Knafels, J., Hobbs, J., Taylor, T., Loucif, A., Konopacka, A., Bell, S., Stevens, E.B., Pandit, J., Horst, R., Withka, J.M., Pryde, D.C., Liu, S., Young, G.T.
Structure