CATH Classification
Level | CATH Code | Description |
---|---|---|
1 | Mainly Alpha | |
1.20 | Up-down Bundle | |
1.20.920 | Histone Acetyltransferase; Chain A | |
1.20.920.10 | Bromodomain-like |
Domain Context
CATH Clusters
Superfamily | Bromodomain-like |
Functional Family | Bromodomain-containing protein 4 |
Enzyme Information
UniProtKB Entries (1)
O60885 |
BRD4_HUMAN
Homo sapiens
Bromodomain-containing protein 4
|
PDB Structure
PDB | 5ULA |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
BET N-terminal bromodomain inhibition selectively blocks Th17 cell differentiation and ameliorates colitis in mice.
Proc. Natl. Acad. Sci. U.S.A.
|