1 keywords

CATH Domain 5ufiD01

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.10 Orthogonal Bundle
Topology 1.10.238 Recoverin; domain 1
Homologous Superfamily 1.10.238.10 EF-hand

Domain Context

CATH Clusters

Superfamily EF-hand
Functional Family DCN1-like protein

Enzyme Information

UniProtKB Entries (1)

Q96GG9
DCNL1_HUMAN
Homo sapiens
DCN1-like protein 1

PDB Structure

PDB 5UFI
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A potent small-molecule inhibitor of the DCN1-UBC12 interaction that selectively blocks cullin 3 neddylation.
Zhou, H., Lu, J., Liu, L., Bernard, D., Yang, C.Y., Fernandez-Salas, E., Chinnaswamy, K., Layton, S., Stuckey, J., Yu, Q., Zhou, W., Pan, Z., Sun, Y., Wang, S.
Nat Commun