CATH Classification

Domain Context

CATH Clusters

Superfamily Cystine-knot cytokines
Functional Family

Enzyme Information

UniProtKB Entries (1)

P61812
TGFB2_HUMAN
Homo sapiens
Transforming growth factor beta-2 proprotein

PDB Structure

PDB 5TX4
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
An engineered transforming growth factor beta (TGF-beta ) monomer that functions as a dominant negative to block TGF-beta signaling.
Kim, S.K., Barron, L., Hinck, C.S., Petrunak, E.M., Cano, K.E., Thangirala, A., Iskra, B., Brothers, M., Vonberg, M., Leal, B., Richter, B., Kodali, R., Taylor, A.B., Du, S., Barnes, C.O., Sulea, T., Calero, G., Hart, P.J., Hart, M.J., Demeler, B., Hinck, A.P.
J. Biol. Chem.