CATH Classification

Domain Context

CATH Clusters

Superfamily FAD/NAD(P)-binding domain
Functional Family

Enzyme Information

1.18.1.2
Ferredoxin--NADP(+) reductase.
based on mapping to UniProt Q2FEC4
2 reduced ferredoxin + NADP(+) + H(+) = 2 oxidized ferredoxin + NADPH.
-!- In chloroplasts and cyanobacteria the enzyme acts on plant-type [2Fe- 2S] ferredoxins, but in other bacteria it can also reduce bacterial 2[4Fe-4S] ferredoxins and flavodoxin. -!- Formerly EC 1.6.7.1 and EC 1.6.99.4.

UniProtKB Entries (1)

Q2FEC4
FENR_STAA3
Staphylococcus aureus subsp. aureus USA300
Ferredoxin--NADP reductase

PDB Structure

PDB 5TWC
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Iron Uptake Oxidoreductase (IruO) Uses a Flavin Adenine Dinucleotide Semiquinone Intermediate for Iron-Siderophore Reduction.
Kobylarz, M.J., Heieis, G.A., Loutet, S.A., Murphy, M.E.P.
ACS Chem. Biol.