CATH Classification

Domain Context

CATH Clusters

Superfamily Neurotransmitter-gated ion-channel ligand-binding domain
Functional Family

Enzyme Information

UniProtKB Entries (2)

Q8WSF8
Q8WSF8_APLCA
Aplysia californica
Soluble acetylcholine receptor
P32297
ACHA3_HUMAN
Homo sapiens
Neuronal acetylcholine receptor subunit alpha-3

PDB Structure

PDB 5TVC
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of a chimeric acetylcholine binding protein from Aplysia californica (Ac-AChBP) containing loop C from the human alpha 3 nicotinic acetylcholine receptor in complex with (E,2S)-N-methyl-5-(5-phenoxy-3-pyridyl)pent-4-en-2-amine (TI-5312)
Bobango, J., Wu, J., Talley, I.T., Talley, T.T.
To Be Published