CATH Classification

Domain Context

CATH Clusters

Superfamily Trypsin-like serine proteases
Functional Family Anionic trypsin

Enzyme Information

3.4.21.4
Trypsin.
based on mapping to UniProt P35030
Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.
-!- Belongs to peptidase family S1. -!- Formerly EC 3.4.4.4.

UniProtKB Entries (1)

P35030
TRY3_HUMAN
Homo sapiens
Trypsin-3

PDB Structure

PDB 5TP0
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Small molecule inhibitors of mesotrypsin from a structure-based docking screen.
Kayode, O., Huang, Z., Soares, A.S., Caulfield, T.R., Dong, Z., Bode, A.M., Radisky, E.S.
PLoS ONE