CATH Classification

Domain Context

CATH Clusters

Superfamily Farnesyl Diphosphate Synthase
Functional Family (2Z,6E)-hedycaryol synthase

Enzyme Information

4.2.3.26
R-linalool synthase.
based on mapping to UniProt D5SL78
Geranyl diphosphate + H(2)O = (3R)-linalool + diphosphate.
-!- Geranyl diphosphate cannot be replaced by isopentenyl diphosphate, dimethylallyl diphosphate, farnesyl diphosphate or geranylgeranyl diphosphate as substrate. -!- Unlike many other monoterpene synthases, only a single product, (3R)- linalool, is formed.

UniProtKB Entries (1)

D5SL78
LNSA_STRC2
Streptomyces clavuligerus ATCC 27064
R-linalool synthase

PDB Structure

PDB 5NX4
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural Basis of Catalysis in the Bacterial Monoterpene Synthases Linalool Synthase and 1,8-Cineole Synthase.
Karuppiah, V., Ranaghan, K.E., Leferink, N.G.H., Johannissen, L.O., Shanmugam, M., Ni Cheallaigh, A., Bennett, N.J., Kearsey, L.J., Takano, E., Gardiner, J.M., van der Kamp, M.W., Hay, S., Mulholland, A.J., Leys, D., Scrutton, N.S.
ACS Catal