CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.420 | Nucleotidyltransferase; domain 5 |
|
3.30.420.330 | Influenza virus non-structural protein, effector domain |
Domain Context
CATH Clusters
| Superfamily | Influenza virus non-structural protein, effector domain |
| Functional Family |
Enzyme Information
UniProtKB Entries (2)
| P03496 |
NS1_I34A1
Influenza A virus (A/Puerto Rico/8/1934(H1N1))
Non-structural protein 1
|
| Q14258 |
TRI25_HUMAN
Homo sapiens
E3 ubiquitin/ISG15 ligase TRIM25
|
PDB Structure
| PDB | 5NT1 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Molecular mechanism of influenza A NS1-mediated TRIM25 recognition and inhibition.
Nat Commun
|