CATH Domain 5mn2C00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.10	Roll
	3.10.450	Nuclear Transport Factor 2; Chain: A,
	3.10.450.10

Domain Context

CATH Clusters

Superfamily	3.10.450.10
Functional Family

Enzyme Information

UniProtKB Entries (1)

FCG3A_HUMAN

Homo sapiens

Low affinity immunoglobulin gamma Fc region receptor III-A

PDB Structure

PDB	5MN2
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Affimer proteins inhibit immune complex binding to Fc gamma RIIIa with high specificity through competitive and allosteric modes of action. Robinson, J.I., Baxter, E.W., Owen, R.L., Thomsen, M., Tomlinson, D.C., Waterhouse, M.P., Win, S.J., Nettleship, J.E., Tiede, C., Foster, R.J., Owens, R.J., Fishwick, C.W.G., Harris, S.A., Goldman, A., McPherson, M.J., Morgan, A.W. Proc. Natl. Acad. Sci. U.S.A.