CATH Classification

Domain Context

CATH Clusters

Superfamily Trypsin-like serine proteases
Functional Family Cationic trypsin

Enzyme Information

3.4.21.4
Trypsin.
based on mapping to UniProt P00760
Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.
-!- Belongs to peptidase family S1. -!- Formerly EC 3.4.4.4.

UniProtKB Entries (1)

P00760
TRY1_BOVIN
Bos taurus
Cationic trypsin

PDB Structure

PDB 5MN1
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Charges Shift Protonation: Neutron Diffraction Reveals that Aniline and 2-Aminopyridine Become Protonated Upon Binding to Trypsin.
Schiebel, J., Gaspari, R., Sandner, A., Ngo, K., Gerber, H.D., Cavalli, A., Ostermann, A., Heine, A., Klebe, G.
Angew. Chem. Int. Ed. Engl.