CATH Classification

Domain Context

CATH Clusters

Superfamily 2.20.28.200
Functional Family NAD-dependent protein deacetylase sirtuin-6

Enzyme Information

3.5.1.-
In linear amides.
based on mapping to UniProt Q8N6T7

UniProtKB Entries (1)

Q8N6T7
SIR6_HUMAN
Homo sapiens
NAD-dependent protein deacetylase sirtuin-6

PDB Structure

PDB 5MF6
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural Basis of Sirtuin 6 Activation by Synthetic Small Molecules.
You, W., Rotili, D., Li, T.M., Kambach, C., Meleshin, M., Schutkowski, M., Chua, K.F., Mai, A., Steegborn, C.
Angew. Chem. Int. Ed. Engl.