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CATH Domain 5m2mC00

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.60 Sandwich
Topology 2.60.120 Jelly Rolls
Homologous Superfamily 2.60.120.40  

Domain Context

CATH Clusters

Superfamily 2.60.120.40
Functional Family Tumor necrosis factor

Enzyme Information

UniProtKB Entries (1)

P01375
TNFA_HUMAN
Homo sapiens
Tumor necrosis factor

PDB Structure

PDB 5M2M
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Bivalent Llama Single-Domain Antibody Fragments against Tumor Necrosis Factor Have Picomolar Potencies due to Intramolecular Interactions.
Beirnaert, E., Desmyter, A., Spinelli, S., Lauwereys, M., Aarden, L., Dreier, T., Loris, R., Silence, K., Pollet, C., Cambillau, C., de Haard, H.
Front Immunol
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